Synthesis of Biologically Decomposable Terpolymer Nanocapsules and Higher?Order Nanoassemblies Using RCMP?PISA

Terpolymers are used to generate bio-decomposable self-assemblies. PEG-PVL-PGMA terpolymers synthesized via a combination of organocatalyzed living radical polymerization (RCMP) with polymerization-induced self-assembly (PISA), generating vesicle, multicompartment micelle (MCM), and core-compartmentalized worm (CCW), where PEG, PVL, PGMA poly(ethylene glycol) monomethyl ether, poly(?-valerolactone), poly(glycidyl methacrylate) is grown during the PISA. MCM CCW uniquely obtainable using terpolymers. The PVL segment biodegradable, obtained assemblies bio-decomposable. Heavy metal-free sulfur-free synthesis bio-decomposability attractive features.